대한흉부영상의학회 Weekly Chest Cases

Figure 1

Diagnosis: Amyloidosis
Radiologic Findings: Contrast enhanced axial chest CT scan showed 4.5cm sized well defined, lobulated, non-enhancing mass with internal multiple calcifications in LUL. Several variable sized calcified or non-calcified nodules are seen in both lungs.
Brief Review: Amyloidosis includes a spectrum of diseases associated with an abnormal extracellular deposition of amyloid, an autologous fibrillar protein material that histochemically binds with Congo red, showing green birefringence in polarized light.
Nodular parenchymal amyloidosis is a rare condition and may be multiple or, much less commonly, single. The patients are usually asymptomatic, rarely presenting with cough, shortness of breath, or hemoptysis. CT demonstrates nodules with sharp and lobulated margins in a peripheral or subpleural location. The size of the nodule varies from micronodular to massive, up to 15 cm in diameter. Calcification is seen in ~50% of cases. The nodules grow slowly, often over years, and do not regress.
References: Kim HY, Im JG, Song KS, Lee KS, et al. Localized amyoidosis of the respiratory system: CT features. J Comput Assist Tomogr. 1999 Jul-Aug; 23(4): 627-31
Keywords: lung, metabolic ans storage,

- University of British Columbia , Canada Amr Ajlan
- Okayama University , Japan Akihiro Tada
- McGill University Health Center , Canada Alexandre Semionov
- GRMC (Gajra raja medical college), deptt. of radiodiagnosis gwalior , India SHAILESH GUPTA
- Diskapi Yildirim Beyazit Hospital, Ankara , Turkey Meric Tuzun
- IRSA , France jean-luc BIGOT
- Youngdong Hospital , Korea (South) Sang Min Lee
- Toyama University Hospital, Laboratory of Pathology , Japan TOMONORI TANAKA
- CHRU lille , France manuel toledano
- Onomichi municipal hospital , Japan Hirofumi Mifune
- Radnet Teleradiology Istanbul , Turkey Armagan Sarac
- Ewha Womans University Hospital , Korea (South) YOOKYUNG KIM
- Fukuyama daiichi Hospital , Japan Mototsugu Saeki
- James Paget Hospital , U.K , United Kingdom nabil mahmood
- IRCCS Istituto Oncologico - Bari , Italy Carlo Florio
- stanley medical college , India arivudai nambi
- IRSA La Rochelle France , France Denis Chabassiere
- Beaulieu clinic Geneva , Switzerland gilles GENIN
- Medical College Chest Hospital,Thrissur,Kerala , India Raveendran TK
- Hotel-Dieu Montreal , Canada nicolas gautier
- All India Institute of medical sciences , India Justin Moses
- Pneumologia Universitaria, Policlinico di Bari , Italy Mario Damiani

대한흉부영상의학회 Korean Society of Thoracic Radiology